Vatalanib hydrochloride - CAS 212141-52-1

Vatalanib hydrochloride (PTK787 hydrochloride) is an orally available and highly potent tyrosine kinase (VEGF) inhibitor that reduces the number and size of Aβ plaques in the cortex of 5xFAD mice, which may be useful in the study of Alzheimer's disease and cancer.

Apoptosis, VEGFR

Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors

212141-52-1

0.997

C20H16Cl2N4

383.27

Cl.ClC1=CC=C(C=C1)NC2=NN=C(C=3C=CC=CC23)CC=4C=CN=CC4

-20°C

Ice Packs

Small Compound