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VB124 - CAS 2230186-18-0
VB124 - CAS 2230186-18-0
SKU:MF-0012953-01
Regular price
$124.13 USD
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$124.13 USD
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Product Details
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Bioactivity
VB124 is an orally active, potent and selective MCT4 inhibitor. VB124 blocked lactate import (IC50 value of 8.6 nM) and export (IC50 value of 19 nM) in MDA-MB-231 cells. VB124 is selective for MCT4 over MCT1 and shows minimal MCT1 inhibitory activity in MCT1-expressing BT20 cells (IC50 value of 24 μM) .
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Target
Monocarboxylate transporter
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
2230168
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Purity
0.9957
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Molecular Formula
C23H23ClN2O4
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Molecular Weight
426.89
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SMILES
CC(C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1Cl)C(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound