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Molfinity

VB124 - CAS 2230186-18-0

VB124 - CAS 2230186-18-0

SKU:MF-0012953-01

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  • Bioactivity

    VB124 is an orally active, potent and selective MCT4 inhibitor. VB124 blocked lactate import (IC50 value of 8.6 nM) and export (IC50 value of 19 nM) in MDA-MB-231 cells. VB124 is selective for MCT4 over MCT1 and shows minimal MCT1 inhibitory activity in MCT1-expressing BT20 cells (IC50 value of 24 μM) .

  • Target

    Monocarboxylate transporter

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    2230168

  • Purity

    0.9957

  • Molecular Formula

    C23H23ClN2O4

  • Molecular Weight

    426.89

  • SMILES

    CC(C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1Cl)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound