VCP746 - CAS 1582751-84-5

VCP-746 is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling. VCP746 reduces hypertrophy in a rat neonatal cardiac myocyte model. VCP746 is a hybrid molecule consisting of an adenosine moiety linked to an adenosine A1 receptor (A1AR) allosteric modulator moiety. At the A1AR, VCP746 mediated cardioprotection in the absence of haemodynamic side effects such as bradycardia.

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Others

1582662

C41H40F3N7O6S

815.86

C(=O)(C=1C(=C(SC1N)C2=CC=C(C(NCCCCCCNC3=C4C(N(C=N4)[C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)=NC=N3)=O)C=C2)C6=CC(C(F)(F)F)=CC=C6)C7=CC=CC=C7

-20°C

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Small Compound