VDR agonist 1 - CAS 2269494-43-9

VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1].

Vitamin, Apoptosis, Others

Apoptosis, Others, Metabolism

2269442

C32H51N3O2

509.77

C(CC)(CC)(C=1C=C(C(NCCN(CC)CC)=O)N(CC)C1)C2=CC(C)=C(/C=C/C(CC)(CC)O)C=C2

-20°C

Ice Packs

Small Compound