VDX-111 - CAS 158983-23-4

VDX-111, an analog of vitamin D, exhibits cytotoxicity in ovarian cancer cells by upregulating the RIPK1/RIPK3 pathway and inducing necroptosis. It also promotes the expression of cytokines and demonstrates antitumor activity in a mouse model [1].

Necroptosis, RIP kinase

Apoptosis, NF-κB

158983-23-4

C29H45BrO4

537.57

C[C@@]12[C@](\C(=C\C=C/3\C[C@@H](OC(CBr)=O)C[C@H](O)C3=C)\CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]

-20°C

Ice Packs

Small Compound