VEGFR-2-IN-23 - CAS 2411174-53-1

VEGFR-2-IN-23 (compound 11b) is a highly potent and selective inhibitor of VEGFR-2, with an IC50 value of 0.34 nM. It demonstrates significant antitumor activity by inducing apoptosis and causing cell cycle arrest at the G1 phase [1].

Others, Apoptosis, VEGFR, MDM-2/p53

Others, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors

2411120

C22H15N5O2

381.39

C(#N)C1=C(C=C(NC1=NN)C2=CC3=C(C=C2)C=CC=C3)C4=CC=C(N(=O)=O)C=C4

-20°C

Ice Packs

Small Compound