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VEGFR-IN-4 - CAS 3000483-29-1
VEGFR-IN-4 - CAS 3000483-29-1
SKU:MF-0121521-01
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Product Details
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Bioactivity
VEGFR-IN-4 (Compound 6e), an inhibitor of the epidermal growth factor receptor (EGFR), demonstrates potent antiproliferative effects with an IC50 value of 24.6nM in HCC827 cells [1].
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Target
EGFR
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Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
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CAS Number
3000483-29-1
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Molecular Formula
C19H19ClN6O3S
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Molecular Weight
446.91
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SMILES
N(C1=C(C(NO)=O)SC=C1)C2=NC(NC3=CC=C(C=C3)N4CCOCC4)=NC=C2Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound