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Molfinity

Verosudil - CAS 1414854-42-4

Verosudil - CAS 1414854-42-4

MF-0014483-01

$49.62 USD
$49.62 USD
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Product Details

  • Bioactivity

    Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 nM and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 mitigates steroid-induced intraocular pressure in mice by decreasing intraocular pressure through enhanced outflow of aqueous humor via the trabecular meshwork.

  • Target

    ROCK

  • Related Pathways

    Cytoskeletal Signaling, Cell Cycle/Checkpoint, Stem Cells

  • CAS Number

    1414808

  • Purity

    0.9972

  • Molecular Formula

    C17H17N3O2S

  • Molecular Weight

    327.4

  • SMILES

    CN(C)C(C(=O)Nc1ccc2c(cc[nH]c2=O)c1)c1ccsc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound