Verrucarin J - CAS 4643-58-7

Verrucarin J (Muconomycin B), derived from the Myrothecium fungus family, effectively generates reactive oxygen species (ROS) to induce apoptosis in various cancer cell lines, including A549, HCT 116, and SW-620. Besides its anticancer properties, it exhibits antifungal activity against Candida albicans and Mucor miehei. Furthermore, it notably inhibits the arenavirus Junin (JUNV) yield with an IC 50 of 1.2 ng/mL.

ROS, Antifungal, Reactive Oxygen Species, Anti-infection, Apoptosis, Others, Virus Protease, Antibiotic

Microbiology/Virology, Apoptosis, Immunology/Inflammation, Metabolism, NF-κB, Others

4578

C27H32O8

484.54

CC1=CC2OC3CC4OC(=O)\C=C/C=C/C(=O)OCC\C(C)=C\C(=O)OCC2(CC1)C4(C)C31CO1

-20°C

Ice Packs

Natural Product