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Verubecestat TFA - CAS 2095432-65-6

Verubecestat TFA - CAS 2095432-65-6

SKU:MF-0145937-01

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  • Bioactivity

    Verubecestat TFA, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat TFA is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat TFA reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.

  • Target

    Others, Beta-Secretase

  • Related Pathways

    Others, Neuroscience

  • CAS Number

    2095361

  • Molecular Formula

    C19H18F5N5O5S

  • Molecular Weight

    523.435

  • SMILES

    OC(=O)C(F)(F)F.CN1C(=N)N[C@@](C)(CS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound