Vesnarinone - CAS 81840-15-5

Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.

HIV Protease, PDE

Microbiology/Virology, Metabolism, Proteases/Proteasome

81820

0.9875

C22H25N3O4

395.45

COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1

-20°C

Ice Packs

Small Compound