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VHL Ligand 14 - CAS 2010986-87-3

VHL Ligand 14 - CAS 2010986-87-3

MF-0121522-01

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Product Details

  • Bioactivity

    VHL Ligand 14 (Compound 11), a VHL ligand engineered for creating PROTAC estrogen receptor α (ERα) degraders, exhibits a binding affinity with an IC50 of 196 nM [1].

  • Target

    Ligand for E3 Ligase

  • Related Pathways

    PROTAC

  • CAS Number

    2010986-87-3

  • Molecular Formula

    C25H34N4O4S

  • Molecular Weight

    486.63

  • SMILES

    C([C@@H](NC(C)=O)C(C)(C)C)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC