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Vismodegib - CAS 879085-55-9
Vismodegib - CAS 879085-55-9
SKU:MF-0012571-01
Regular price
$38.41 USD
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$38.41 USD
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Product Details
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Bioactivity
Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM) . It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM) .
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Target
ABC Transporter, Autophagy, Hedgehog/Smoothened
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Related Pathways
GPCR/G Protein, Membrane transporter/Ion channel, Stem Cells, Autophagy
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CAS Number
879021
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Purity
0.9999
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Molecular Formula
C19H14Cl2N2O3S
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Molecular Weight
421.3
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SMILES
ClC=1C(=CC(NC(=O)C2=C(Cl)C=C(S(C)(=O)=O)C=C2)=CC1)C3=CC=CC=N3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound