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VISTA-IN-3 - CAS 2994662-45-0

VISTA-IN-3 - CAS 2994662-45-0

MF-0121525-01

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Product Details

  • Bioactivity

    VISTA-IN-3 (Compound A4), a potent small molecule inhibitor of VISTA, exhibits a dissociation constant (K D) of 0.49 μM. This compound effectively induces the release of IFN-γ cytokines and demonstrates synergistic enhancement of anti-cancer activity when combined with PD-L1 antibody [1].

  • Target

    IFNAR

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2994662-45-0

  • Molecular Formula

    C14H18N4O3

  • Molecular Weight

    290.32

  • SMILES

    N(C=1N=C(CNCCO)C=C(OC)N1)C2=CC(O)=CC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound