VNRX-9945 - CAS 2396680-45-6

VNRX-9945 is a potent and orally active HBV capsid assembly modulator (CAM), exhibiting an EC50 value of 2.6 nM. It demonstrates excellent and broad-spectrum antiviral activity against multiple HBV genotypes in vitro, with favorable pharmacokinetic properties across various species. Additionally, VNRX-9945 shows significant antiviral efficacy in the AAV-HBV infected mouse model.

HBV

Microbiology/Virology

2396629

C23H28FN3O4

429.48

C(C(N[C@@H]1CC[C@H](O)CC1)=O)(=O)C2=C(C)C(C(NC3=CC(C)=C(F)C=C3)=O)=C(C)N2C

-20°C

Ice Packs

Small Compound