VO-OHPic - CAS 675848-25-6

VO-OHPic is a reversible, noncompetitive, and selective inhibitor of PTEN with an IC50 of 46 nM, effectively attenuating apoptosis, adverse cardiac remodeling, and the presence of pro-inflammatory M1 macrophages in models of doxorubicin-induced cardiomyopathy. Additionally, VO-OHPic inhibits autophagy [1] [2] [3].

Others, Autophagy, PTEN, Apoptosis

Autophagy, Apoptosis, Others, PI3K/Akt/mTOR signaling

675817

C12H10N2O8V

361.16

[O-][V]=O.OC(=O)c1ncccc1O.OC(=O)c1ncccc1O

-20°C

Ice Packs

Small Compound