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Vofopitant dihydrochloride - CAS 168266-51-1

Vofopitant dihydrochloride - CAS 168266-51-1

SKU:MF-0013048-01

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  • Bioactivity

    Vofopitant dihydrochloride (GR 205171A) is an orally available, selective tachykinin NK1 receptor antagonist that inhibits [3H]SP binding to NK1 with pKi values of 9.5 and 10.6, respectively. It is a potential compound for the treatment of pathological vomiting.

  • Target

    Neurokinin receptor

  • Related Pathways

    GPCR/G Protein, Neuroscience

  • CAS Number

    168214

  • Purity

    0.9899

  • Molecular Formula

    C21H25Cl2F3N6O

  • Molecular Weight

    505.36

  • SMILES

    Cl.Cl.COc1ccc(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)-n1nnnc1C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound