Vonoprazan hydrochloride - CAS 1957202-44-6

Vonoprazan hydrochloride, a proton pump inhibitor (PPI), effectively functions as a potassium-competitive acid blocker (P-CAB) with potent antisecretory properties. It significantly inhibits H+, K+-ATPase activity in porcine gastric microsomes, displaying an IC50 of 19 nM at pH 6.5. Developed primarily for researching acid-related conditions such as gastroesophageal reflux disease and peptic ulcer disease, vonoprazan hydrochloride also aids in the eradication of Helicobacter pylori [1] [2] [3].

Proton pump, Others, Antibacterial

Others, Membrane transporter/Ion channel, Microbiology/Virology

1957152

C17H17ClFN3O2S

381.85

Cl.CNCc1cc(-c2ccccc2F)n(c1)S(=O)(=O)c1cccnc1

-20°C

Ice Packs

Small Compound