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Molfinity

Voxelotor - CAS 1446321-46-5

Voxelotor - CAS 1446321-46-5

SKU:MF-0017368-01

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  • Bioactivity

    Voxelotor (GBT 440) is a novel hemoglobin S (HbS) polymerization inhibitor primarily used for the treatment of sickle cell disease (SCD) and a cytochrome P450 3A4 inhibitor. Voxelotor targets and covalently binds to the N-terminal valine of the HbS alpha chain, thereby stabilizing sickle cell hemoglobin (HbS) .

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1446270

  • Purity

    0.9994

  • Molecular Formula

    C19H19N3O3

  • Molecular Weight

    337.37

  • SMILES

    CC(C)n1nccc1-c1ncccc1COc1cccc(O)c1C=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound