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Voxelotor - CAS 1446321-46-5
Voxelotor - CAS 1446321-46-5
SKU:MF-0017368-01
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$41.39 USD
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$41.39 USD
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Product Details
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Bioactivity
Voxelotor (GBT 440) is a novel hemoglobin S (HbS) polymerization inhibitor primarily used for the treatment of sickle cell disease (SCD) and a cytochrome P450 3A4 inhibitor. Voxelotor targets and covalently binds to the N-terminal valine of the HbS alpha chain, thereby stabilizing sickle cell hemoglobin (HbS) .
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Target
Others
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Related Pathways
Others
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CAS Number
1446270
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Purity
0.9994
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Molecular Formula
C19H19N3O3
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Molecular Weight
337.37
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SMILES
CC(C)n1nccc1-c1ncccc1COc1cccc(O)c1C=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound