VR23 - CAS 1624602-30-7

VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.

Proteasome, Apoptosis, Caspase

Apoptosis, Ubiquitination, Proteases/Proteasome

1624565

0.9962

C19H16ClN5O6S

477.88

[O-][N+](=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12

-20°C

Ice Packs

Small Compound