VRK1/CK1-IN-1 - CAS 3050772-20-5

VRK1/CK1-IN-1 (compound 36) is a dual inhibitor targeting vaccinia-related kinase 1 (VRK1) and casein kinase 1 (CK1), with a Ki of 37.9 nM for VRK1. It exhibits IC50 values of 17 nM and 15 nM for CK1 δ and ε isoforms, respectively.

Casein Kinase

Metabolism, Stem Cells

3050747

C19H18F2N6O3

416.38

C(N1C=2C(=NC(NC3=CC(F)=C(O)C(F)=C3)=NC2)N(C)[C@@H](C)C1=O)C=4ON=C(C)C4

-20°C

Ice Packs

Small Compound