VTP50469 fumarate - CAS 2169919-29-1

VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.

Others, Apoptosis, Epigenetic Reader Domain

Chromatin/Epigenetic, Others, Apoptosis

2169889

C76H106F2N12O20S2

1609.86

OC(/C=C/C(O)=O)=O.CC(C)N(C(C)C)C(C(C=C(C=C1)F)=C1OC2=CN=CN=C2N(C3)CC3(CC4)CCN4C[C@@H]5CC[C@H](CC5)NS(C)(=O)=O)=O.CC(C)N(C(C)C)C(C(C=C(C=C6)F)=C6OC7=CN=CN=C7N(C8)CC8(CC9)CCN9C[C@@H]%10CC[C@H](CC%10)NS(C)(=O)=O)=O.OC(/C=C/C(O)=O)=O.OC(/C=C/C(O)=O)=O

-20°C

Ice Packs

Small Compound