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VU 0546110 - CAS 1421523-00-3
VU 0546110 - CAS 1421523-00-3
SKU:MF-0119825-01
Regular price
$423.81 USD
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$423.81 USD
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Product Details
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Bioactivity
VU 0546110, a selective inhibitor of the sperm-specific potassium channel SLO3 (IC50= 64 μM), demonstrates 40-fold selectivity over SLO1. It effectively blocks both heterologous SLO3 currents and endogenous K+ currents, inhibiting sperm hyperpolarization and preventing hyperactivated mobility.
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Target
Others, Potassium Channel
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Related Pathways
Others, Membrane transporter/Ion channel
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CAS Number
1421523-00-3
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Molecular Formula
C24H31NO4S2
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Molecular Weight
461.64
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SMILES
COC1=CC=C(SCC2CCN(CC2)C(=O)CC2=CC=C(C=C2)S(=O)(=O)C(C)C)C=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound