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Molfinity

VU 0546110 - CAS 1421523-00-3

VU 0546110 - CAS 1421523-00-3

SKU:MF-0119825-01

Regular price $423.81 USD
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  • Bioactivity

    VU 0546110, a selective inhibitor of the sperm-specific potassium channel SLO3 (IC50= 64 μM), demonstrates 40-fold selectivity over SLO1. It effectively blocks both heterologous SLO3 currents and endogenous K+ currents, inhibiting sperm hyperpolarization and preventing hyperactivated mobility.

  • Target

    Others, Potassium Channel

  • Related Pathways

    Others, Membrane transporter/Ion channel

  • CAS Number

    1421523-00-3

  • Molecular Formula

    C24H31NO4S2

  • Molecular Weight

    461.64

  • SMILES

    COC1=CC=C(SCC2CCN(CC2)C(=O)CC2=CC=C(C=C2)S(=O)(=O)C(C)C)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound