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Molfinity

VU0361737 - CAS 1161205-04-4

VU0361737 - CAS 1161205-04-4

MF-0018590-01

$31.68 USD
$31.68 USD
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Product Details

  • Bioactivity

    VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of the mGlu4 receptor with an EC50 of 240 nM for human receptors and 110 nM for rat receptors. It exhibits weak activity at mGlu5 and mGlu8 receptors and is inactive at mGlu1, mGlu2, mGlu3, mGlu6, and mGlu7 receptors. The compound can penetrate the CNS.

  • Target

    GluR

  • Related Pathways

    Neuroscience

  • CAS Number

    1161205-04-4

  • Purity

    0.9986

  • Molecular Formula

    C13H11ClN2O2

  • Molecular Weight

    262.69

  • SMILES

    COc1cc(NC(=O)c2ccccn2)ccc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound