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Molfinity

VU0448088 - CAS 1417616-42-2

VU0448088 - CAS 1417616-42-2

SKU:MF-0148260-01

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  • Bioactivity

    VU0448088 (ML253) is a potent positive allosteric modulator of the tricyclic muscarinic acetylcholine receptor subtype 4 (M4) and can cross the blood-brain barrier. It exhibits EC50 values of 56 nM and 176 nM in humans and rats, respectively. The compound VU0448088 holds potential for use in psychiatric research.

  • Target

    AChR

  • Related Pathways

    Neuroscience

  • CAS Number

    1417616-42-2

  • Molecular Formula

    C16H15ClN4OS

  • Molecular Weight

    346.83

  • SMILES

    O=C(NCC=1C=CN=CC1)C=2SC3=NC(=C(Cl)C(=C3C2N)C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound