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VU0448088 - CAS 1417616-42-2
VU0448088 - CAS 1417616-42-2
SKU:MF-0148260-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
VU0448088 (ML253) is a potent positive allosteric modulator of the tricyclic muscarinic acetylcholine receptor subtype 4 (M4) and can cross the blood-brain barrier. It exhibits EC50 values of 56 nM and 176 nM in humans and rats, respectively. The compound VU0448088 holds potential for use in psychiatric research.
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Target
AChR
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Related Pathways
Neuroscience
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CAS Number
1417616-42-2
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Molecular Formula
C16H15ClN4OS
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Molecular Weight
346.83
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SMILES
O=C(NCC=1C=CN=CC1)C=2SC3=NC(=C(Cl)C(=C3C2N)C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound