1 1

Molfinity

VU0463271 - CAS 1391737-01-1

VU0463271 - CAS 1391737-01-1

MF-0019808-01

$42.14 USD
$42.14 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    VU0463271 (N-Cyclopropyl-N- (4-methyl-2-thiazolyl) -2-[ (6-phenyl-3-pyridazinyl) thio]acetamide) is a potent and selective antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2), with an IC50 of 61 nM and >100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1) and no activity in a larger panel of GPCRs, ion channels, and transporters.

  • Target

    Potassium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    1391737-01-1

  • Purity

    0.9975

  • Molecular Formula

    C19H18N4OS2

  • Molecular Weight

    382.5

  • SMILES

    Cc1csc(n1)N(C1CC1)C(=O)CSc1ccc(nn1)-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound