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VU0467485 - CAS 1451994-10-7
VU0467485 - CAS 1451994-10-7
SKU:MF-0034312
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$88.38 USD
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$88.38 USD
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Product Details
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Bioactivity
VU0467485 is a potent and selective muscarinic acetylcholine receptor 4 positive allosteric modulator. VU0467485 potentiates the activity of ACh at M4 (EC50s: 26.6 nM and 78.8 nM at the rat and human M4 receptors, respectively) . VU0467485 displays selectivity for M4 over human and rat M1/2/3/5.
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Target
AChR, Others
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Related Pathways
Others, Neuroscience
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CAS Number
1451977
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Molecular Formula
C17H17FN4O2S
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Molecular Weight
360.41
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SMILES
COc1ccc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound