VU0506013 - CAS 1207036-87-0

VU0506013 is a high-affinity positive allosteric modulator (PAM) of the neuropeptide Y4 receptor. This compound demonstrates nanomolar-level affinity and notable selectivity in engineered cell lines and the descending colon mucosa of mice that naturally express Y4R. VU0506013 presents a promising foundation for developing in vivo tools aimed at advancing anti-obesity compound research targeting Y4R.

Neuropeptide Y Receptor

Neuroscience, GPCR/G Protein

1207036-87-0

C20H23N3O4

369.41

O=C(C=1C=C(NC(=O)COC=2C=CC=CC2C)C(=O)N(C1)C)N3CCCC3

-20°C

Ice Packs

Peptide