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VU591 hydrochloride - CAS 1315380-70-1

VU591 hydrochloride - CAS 1315380-70-1

MF-0012038-01

$32.42 USD
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Product Details

  • Bioactivity

    VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM) . Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590

  • Target

    Potassium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    1315380-70-1

  • Purity

    0.9995

  • Molecular Formula

    C16H13ClN6O5

  • Molecular Weight

    404.76

  • SMILES

    Cl.[O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound