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VU6043653 - CAS 3032791-06-0
VU6043653 - CAS 3032791-06-0
SKU:MF-0110919-01
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Product Details
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Bioactivity
VU6043653 is an effective, selective, and blood-brain barrier-permeable negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5), with an IC50 value of 325 nM against h mGlu5.
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Target
ROCK, HDAC
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Related Pathways
Chromatin/Epigenetic, Stem Cells, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Cytoskeletal Signaling
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CAS Number
3032791-06-0
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Molecular Formula
C16H14FN5O2
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Molecular Weight
327.31
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SMILES
O=C(NC1=NC=C(F)C=C1)C=2N=C(C=C(OC=3C=NN(C3)C)C2)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound