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Molfinity

VUF14480 - CAS 1605304-31-1

VUF14480 - CAS 1605304-31-1

MF-0144798-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    VUF14480 is a covalent partial agonist that interacts with cysteine 98 (3.36) of the human histamine H4 receptor. VUF14480 was shown to be a partial agonist of hH4 receptor-mediated G protein signalling and β-arrestin2 recruitment. VUF14480 bound covalently to the hH4 receptor with submicromolar affinity. Serine substitution of C98 (3.36) prevented this covalent interaction.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1605272

  • Molecular Formula

    C17H20N4

  • Molecular Weight

    280.37

  • SMILES

    C(=C)C=1N=C(C=C(N1)C2=CC=CC=C2)N3CCN(C)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound