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VVD-118313 - CAS 2875046-27-6

VVD-118313 - CAS 2875046-27-6

MF-0042096-01

$4,832.38 USD
$4,832.38 USD
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Product Details

  • Bioactivity

    VVD-118313 (compound 5a), a potent, selective JAK1 inhibitor, targets an isoform-restricted allosteric cysteine to inhibit JAK1-dependent trans-phosphorylation and cytokine signaling. This compound is utilized in cancer research [1].

  • Target

    STAT, JAK, Interleukin, Others, IFNAR

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Stem Cells, Immunology/Inflammation, Others, Chromatin/Epigenetic

  • CAS Number

    2875013

  • Molecular Formula

    C19H22Cl2N2O3S

  • Molecular Weight

    429.36

  • SMILES

    C(C#C[C@@H]1CN(S(C)(=O)=O)CC1)(=O)N2C[C@@H](CCC2)C3=CC(Cl)=C(Cl)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound