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VVD-442 - CAS 3055318-88-9
VVD-442 - CAS 3055318-88-9
SKU:MF-0119384-01
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Product Details
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Bioactivity
VVD-442 is a covalent RAS-PI3K inhibitor that binds covalently to cysteine at position 242 in the RAS-binding domain of PI3Kp110α, thereby inhibiting the interaction between RAS and PI3K. VVD-442 is applicable for research in cancers such as breast cancer.
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Target
Ras, PI3K
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Related Pathways
PI3K/Akt/mTOR signaling, MAPK
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CAS Number
3055221
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Molecular Formula
C23H25BrClFN2O5S2
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Molecular Weight
607.94
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SMILES
S(=O)(=O)(C1=C(C=C(Br)C=C1)C2=C(Cl)C=CC=C2)N3CCC(C(N[C@@H](/C=C\S(C)(=O)=O)C)=O)(F)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound