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Molfinity

VX-984 - CAS 1476074-39-1

VX-984 - CAS 1476074-39-1

SKU:MF-0018085-01

Regular price $127.38 USD
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  • Bioactivity

    VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSC-LC) studies.

  • Target

    DNA-PK

  • Related Pathways

    PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

  • CAS Number

    1476034

  • Purity

    0.9998

  • Molecular Formula

    C23H21D2N7O

  • Molecular Weight

    415.49

  • SMILES

    [2H]c1nc(C)nc([2H])c1-c1cc(NC[C@@H](C)c2cccc3c(ccnc23)C(=O)NC)ncn1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Isotope products