W23-1006 - CAS 3035498-92-8

W23-1006 is a selective covalent ALKBH5 inhibitor. It binds to the ALKBH5 C200 residue with an IC50 value of 3.848 μM. The inhibitory activity of W23-1006 is approximately 30 times stronger than that of FTO and 8 times greater than that of ALKBH3. W23-1006 is applicable for research in triple-negative breast cancer (TNBC) .

Apoptosis, ALK

Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis

3035398

C17H12BrN3O5

418.198

O=C1NN(C(=O)C1=CC2=CC(Br)=CC(=C2)N(=O)=O)C3=CC=C(OC)C=C3

-20°C

Ice Packs

Small Compound