WAY 163909 hydrochloride - CAS 428868-35-3

WAY 163909 hydrochloride is an effective agonist for the serotonin 5-HT2C receptor, with an EC50 value of 8 nM and a maximal efficacy of 90%. It shows minimal activity at the 5-HT2A receptor. The compound displays its selectivity with a Ki value of 10.5 nM at the 5-HT2C receptor, compared to higher Ki values at 5-HT2A (212 nM), 5-HT7 (343 nM), and 5-HT2B (485 nM) receptors, and it lacks significant activity at various other receptors.

5-HT Receptor

Neuroscience, GPCR/G Protein

428830

C14H19ClN2

250.77

C1=2C=3[C@@]4([C@](N1CCNCC2C=CC3)(CCC4)[H])[H].Cl

-20°C

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