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WAY-600 - CAS 1062159-35-6
WAY-600 - CAS 1062159-35-6
SKU:MF-0018230-01
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Product Details
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Bioactivity
WAY-600 is a potent, ATP-competitive, and selective inhibitor of mTOR with an IC50 of 9 nM; it blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) but not P-AKT (T308), and is selective for mTOR over PI3Kα (>100-fold) and PI3Kγ (>500-fold) .
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Target
Src, mTOR, VEGFR, PI3K
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Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling
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CAS Number
1062118
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Purity
0.9988
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Molecular Formula
C28H30N8O
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Molecular Weight
494.59
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SMILES
C(N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc2[nH]ccc2c1)N1CCOCC1)c1cccnc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound