WDR5 degrader-1 - CAS 3032434-45-7

WDR5degrader-1 is a cereblon (CRBN) degrader that recruits WDR5. It selectively targets CRBN's new substrate IKZF1 for the degradation of WDR5.

PROTACs, JAK

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling, Stem Cells, Chromatin/Epigenetic, PROTAC

3032382

C49H52F4N8O9

972.98

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCCCNC(=O)C4=CC(=C(F)C=C4)C5=CC(NC(=O)C=6C(C(F)(F)F)=CC(=O)NC6)=C(C=C5)N7C[C@@H](C)N(C)[C@@H](C)C7)=O

-20°C

Ice Packs

PROTAC