WEE1-IN-11 - CAS 2975172-98-4

WEE1-IN-11 (Compound 13) serves as a potent CDK2 inhibitor with an IC50 of 2.0 nM. It exhibits inhibitory effects on several cell lines, including NCI-H446, A427, OVCAR3, C33A, and WiDr, with respective IC50 values of 93.9, 34.5, 86.7, 23.1, and 85 nM.

Wee1

Cell Cycle/Checkpoint

2975070

C26H29FN8OS2

552.69

N(C=1N=C(C(=CN1)C2=CN=CS2)C=3SC(=NC3)N4CC[C@H](F)C4)C5=CC(OC)=C(C=C5)N6CCN(C)CC6

-20°C

Ice Packs

Small Compound