WIN 66306 - CAS 151928-32-4

WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated guinea pig ileum in a concentration-dependent manner.

Others, Neurokinin receptor

Neuroscience, GPCR/G Protein, Others

151892

C41H52N8O9

800.9

CC(C)[C@H](NC(=O)CNC(=O)[C@@H]1CC=CN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)C(=O)NCC(=O)N[C@H](C=O)[C@H](O)c1ccc(O)c(CC=C(C)C)c1

-20°C

Ice Packs

Peptide