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WIZ degrader 1 - CAS 2839552-68-8

WIZ degrader 1 - CAS 2839552-68-8

SKU:MF-0148252-01

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  • Bioactivity

    WIZ degrader 1 (Compound 141) is a degrader of the wide-interval zinc-finger motif (WIZ) with an AC50 of 2 nM. It can induce the expression of fetal hemoglobin (HbF), exhibiting an EC50 value of 6 mM. WIZ degrader 1 is used in the research of genetic blood disorders.

  • Target

    Histone Methyltransferase, Others

  • Related Pathways

    Others, Chromatin/Epigenetic

  • CAS Number

    2839552-68-8

  • Molecular Formula

    C25H33F2N5O2

  • Molecular Weight

    473.56

  • SMILES

    C(C1=CC2=C(C=NN2C=C1)N3C(=O)NC(=O)CC3)[C@H]4C[C@H](C)N(CC5CCC(F)(F)CC5)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound