WIZ degrader 3 - CAS 2839637-72-6

WIZ degrader 3 (Compound 29) is a degrader of the wide-interval zinc finger motif (WIZ) with an AC50 of 6.4 nM. It induces the expression of fetal hemoglobin (HbF) with an EC50 of 45 nM. This compound is useful for the study of blood disorders such as sickle cell disease and β-thalassemia.

2839637-72-6

C18H23N5O3

357.41

C(C=1C=C2C(=NOC2=CC1)N3C(=O)NC(=O)CC3)N4C[C@H](C)N(C)CC4

-20°C

Ice Packs

Small Compound