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WIZ degrader 8 - CAS 2879251-26-8

WIZ degrader 8 - CAS 2879251-26-8

MF-0113272-01

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Product Details

  • Bioactivity

    WIZ degrader 8 (compound 10) is a potent and selective molecular glue degrader of the transcription factor WIZ, effectively inducing HbF expression. It promotes WIZ degradation and HbF induction, suggesting its potential use as an inhibitor for sickle cell disease.

  • Target

    Histone Acetyltransferase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    2879217

  • Molecular Formula

    C21H27N3O4

  • Molecular Weight

    385.457

  • SMILES

    O=C1N(CC=2C1=CC=C(O[C@H]3CN(CC)C[C@H](C)C3)C2)C4C(=O)NC(=O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound