WJ-39 - CAS 3009908-95-3

WJ-39 is an orally active aldose reductase (AR) inhibitor that ameliorates renal lesions in diabetic nephropathy through activation of Nrf2 signaling, and may be used to ameliorate renal insufficiency and fibrosis.WJ-39 inhibits oxidative stress and inhibits the activation of the inflammatory vesicle of the oligomerization structural domain-like receptor family, pyrin structural domain 3 (NLRP3) .

Mitophagy, Reductase, Apoptosis, Mitochondrial Metabolism

Autophagy, Endocrinology/Hormones, Apoptosis, Metabolism

3009908-95-3

0.9945

C19H14Cl2KNO4

430.32

O=C(CN1C=C(CC2=C(Cl)C(Cl)=CC=C2)C(C3=CC(OC)=CC=C31)=O)[O-].[K+]

-20°C

Ice Packs

Small Compound