WLB-89462 - CAS 2849471-75-4

WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 nM, demonstrating neuroprotective properties and the capacity to ameliorate Aβ peptide-induced short-term memory impairment in rats. It exhibits a favorable ADMET profile, featuring good solubility, lack of CYP inhibition, strong metabolic stability, high permeability, effective brain penetration, and significant oral exposure in rodent models [1].

Sigma receptor

GPCR/G Protein

2849392

C21H29N5O3

399.49

C(C)C=1N=C(C(=CN1)C2=CC(C)=NO2)C3CCN(CC(=O)N4CCOCC4)CC3

-20°C

Ice Packs

Small Compound