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Molfinity

WM-586 - CAS 2894832-05-2

WM-586 - CAS 2894832-05-2

MF-0157025-01

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Product Details

  • Bioactivity

    WM-586 is a covalent inhibitor of WDR5 that impedes the WDR5-MYC binding. It selectively reduces the interaction between WDR5 and MYC with an IC50 value of 101 nM, as determined by the HTRF assay [1].

  • Target

    Histone Methyltransferase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    2894832-05-2

  • Molecular Formula

    C20H20F3N5O3S

  • Molecular Weight

    467.47

  • SMILES

    FC1=C(C[C@@H](CCCC)C(=O)NC2=NN=NN2)C(F)=CC(C2C=CC=C(S(=O)(=O)F)C=2)=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound