WMS-1405 - CAS 1232196-73-4

WMS-1405 is a derivative of ifenprodil. As a potent NR2B-selective NMDA receptor antagonist, it exhibits a Ki value of 5.4 nM. Synthesized through a central building block approach, WMS-1405 displays high NR2B affinity due to the specific distance between its basic nitrogen atom and phenyl residue. WMS-1405 has the potential to serve as an NMDA antagonist for excitotoxicity treatment.

1232119

C21H27NO2

325.45

OC1C2=CC=C(OC)C=C2CCN(CCCCC=3C=CC=CC3)C1

-20°C

Ice Packs

Small Compound