Wnt/β-catenin-IN-3 - CAS 1809413-98-6

Wnt/β-catenin-IN-3 (compound 17), a Wnt/β-catenin inhibitor, exhibits low micromolar GI 50 s across different cancer cell lines. It induces G2/M cell cycle arrest through the activation of the p53-p21 pathway and promotes both intrinsic and extrinsic apoptotic death in colon cancer cells [1].

MDM-2/p53, Wnt/beta-catenin

Cytoskeletal Signaling, Apoptosis, Stem Cells

1809413-98-6

C26H23NO7

461.46

O(C)C1=C2C(OC(=CC2=O)C3=CC(NC(=O)C4=CC=C(OC)C=C4)=CC=C3)=CC(OC)=C1OC

-20°C

Ice Packs

Small Compound