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WNTinib - CAS 2770091-44-4

WNTinib - CAS 2770091-44-4

MF-0121537-01

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Product Details

  • Bioactivity

    WNTinib (APS-8-100-2), a multi-kinase inhibitor, selectively targets β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC) and impedes oncogenic Wnt signaling. It achieves this by inhibiting KIT/MAPK and subsequent activation of EZH2 [1].

  • Target

    Apoptosis, Wnt/beta-catenin

  • Related Pathways

    Cytoskeletal Signaling, Apoptosis, Stem Cells

  • CAS Number

    2770091-44-4

  • Molecular Formula

    C22H16F6N4O3

  • Molecular Weight

    498.38

  • SMILES

    O(C=1C=C(C(NC)=O)N=CC1)C2=CC(F)=C(NC(NC3=CC=C(C(C(F)(F)F)(F)F)C=C3)=O)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound