Wortmannin - CAS 19545-26-7

Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.

Antibiotic, PI3K, Serine/threonin kinase, Autophagy, ATM/ATR, PLK, DNA-PK

Metabolism, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Autophagy, DNA Damage/DNA Repair, Microbiology/Virology

19512

0.9977

C23H24O8

428.43

C[C@@]12C3=C([C@]4([C@](C)(C[C@H]3OC(C)=O)C(=O)CC4)[H])C(=O)C5=C1C(C(=O)O[C@@H]2COC)=CO5

-20°C

Ice Packs

Small Compound